IMMUNOL. TODAY 13/6 (1992) 219-224

The role of nasopharyngeal lymphoid tissue

Kuper C.F., Koornstra P.J., Hameleers D.M.H., Biewenga J., Spit B.J. , Duijvestijn A.M., Van Breda Vriesman P.J.C., Sminia T.

Laboratory of Pathology, Nat.Inst.Public Hlth/Env.Protection, PO Box 1, 3720 BA Bilthoven, Netherlands

Abstract
Nasal-associated lymphoid tissue (NALT), which comprises paired lymphoid organs in the nasopharynx of rodents, is the principal mucosal lymphoid tissue of the respiratory tract. As described in this review, NALT bears certain similarities to the Peyer's patches of the intestine but the two differ remarkably in morphology, lymphoid migration patterns and the binding properties of their high endothelial venules (HEV).

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